Perception and determinants of Social Networking Sites (SNS) on spreading awareness and panic during the COVID-19 pandemic in BangladeshResearch article Published on 2022-12-012022-10-05 Journal: Health Policy OPEN [Category] 치료기술, [키워드] assist Awareness Bangladesh Chi-square collected COVID-19 COVID-19 pandemic determinant determine Facebook form Google highest information Logistic regression Logistic regression analysis media medium misinformation multivariate networking pandemic Panic participant Pearson Perception performed Prevent regulate Research Result reveal significantly Site social media Social networking site Spread survival unique variable variables [DOI] 10.1016/j.hpopen.2022.100075 [Article Type] Research article
Association of iron-related biomarkers with severity and mortality in COVID-19 patientsArticle Published on 2022-12-012022-11-15 Journal: Journal of trace elements in medicine and biology [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] Activation Analysis analyzed association AUC biological processes Biomarker can be used characterized Combination continuous monitoring contribute Control controls Course COVID COVID 19 COVID-19 COVID-19 patient cutoff point Deceased decrease deficiency demonstrated discharged ferritin healthy individual highest IL-6 immune responses immune system immunomodulatory individual infected with COVID-19 Infection Inflammation iron marker material Mild moderate Mortality multiple regression model outcome oxidative stress parameter patients with COVID-19 receiver operating characteristic recruited regulate required ROC ROC Curve SARS-CoV-2 patients sensitivity serum severe disease severity shown significant difference significantly significantly increased specificity stepwise AIC selection survival susceptibility the cytokine storm the median trace Trace element Trace metals Transferrin Transferrin. variable variety viral infections [DOI] 10.1016/j.jtemb.2022.127075 PMC 바로가기
Epistasis-Driven Evolution of the SARS-CoV-2 Secondary StructureArticle Published on 2022-12-012022-11-16 Journal: Journal of molecular evolution [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome arises arising base pairs Compensatory Compensatory evolution conserved coronavirus Deleterious derived allele epistasis Evolution form Frequency functional genetic background Genome highlight Hydrogen bond Hypothesis Last Modification motif Mutation natural selection pathogenicity regulate RNA SARS-CoV-2 secondary secondary structure Secondary structure. Structure target the SARS-CoV-2 UTR viral replication [DOI] 10.1007/s00239-022-10073-1 PMC 바로가기
The association between social media use and hesitancy toward COVID-19 vaccine booster shots in China: A web-based cross-sectional survey중국에서 소셜 미디어 사용과 COVID-19 백신 부스터 접종에 대한 주저의 연관성: 웹 기반 횡단면 조사Article Published on 2022-11-302022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI adjusted odds ratio association booster booster shot China conducted content COVID-19 COVID-19 vaccine cross-sectional cross-sectional study cross-sectional survey effort evaluate health information Hesitancy hesitancy rate Immunity information knowledge media misinformation monthly income participant platform questionnaire regulate response rate SARS-CoV-2 variants social media third dose unemployment Vaccine Vaccine hesitancy vaccine hesitancy. [DOI] 10.1080/21645515.2022.2065167 PMC 바로가기 [Article Type] Article
Recent advances in applying G-quadruplex for SARS-CoV-2 targeting and diagnosis: A reviewArticle Published on 2022-11-302022-11-15 Journal: International journal of biological macromolecules [Category] SARS, 변종, 치료기술, 치료제, [키워드] accumulating addressed antiviral drug Care caused coronavirus SARS-CoV-2 diagnostic functions G-quadruplex Health Host Immune escape Intervention Ligand ligands neutralizing antibody nucleic acid pandemic polymerases protease Protein question recent regulate SARS-CoV-2 SARS-CoV-2 detection Structure targeting Targeting. Treatment strategies Vaccine variant virus virus [DOI] 10.1016/j.ijbiomac.2022.09.152 PMC 바로가기
Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cellsArticle Published on 2022-11-022022-11-15 Journal: The EMBO Journal [Category] COVID19(2023년), SARS, 진단, [키워드] Affect analyses autophagy Better boost cancer cell cancer cell lines Cell cell type ciliated conducted COVID-19 pathology COVID19 Critical eight endocytosed enterocytes experiment expressed Factor Genetic genetic screen Gut help Host host cell human cell human lung identify impair Infection Interaction lentiviruses loss-of-function lysosomal lysosomal membrane overexpression plac8 plasma Protein regulate respiratory tract SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV-2 viruses secretory cell single-cell SPNS1 spns1. susceptible viral entry viral infection virions [DOI] 10.15252/embj.2022110727 PMC 바로가기
Transcriptional regulation and small compound targeting of ACE2 in lung epithelial cellsArticle Published on 2022-11-012022-11-15 Journal: Acta pharmacologica Sinica [Category] COVID19(2023년), SARS, 진단, [키워드] 16HBE 16HBE cell 16HBE cells 6-O-angeloylplenolin ACE2 ACE2 expression addition administration Cell Centipeda Centipeda minima chemokine Chinese Compound conducted COVID-19 CX3CL1 CXCL13 dataset demonstrated downregulated entry of SARS-CoV-2 enzyme evaluated expression gene encoding HLF IL-6 inhibited inhibitor Interaction lung epithelial cell Lung epithelial cells lung tissue lung tissues mice modulate parental pathogen phosphorylated positively correlated promoter PROTECT Protein pseudovirus receptor reduced regulate Regulation S protein SARS-CoV-2 SARS-COV-2 infection screened STAT3 STAT3. stimulated suppressed target cells tested TFS Transcription transcription factor transfected with [DOI] 10.1038/s41401-022-00906-6 PMC 바로가기
CASA: a comprehensive database resource for the COVID-19 Alternative Splicing AtlasArticle Published on 2022-10-202022-11-15 Journal: Journal of Translational Medicine [Category] 유전자 메커니즘, 치료기술, 치료제, [키워드] affected alteration Analysis Atla cell line conditions COVID-19 database dataset Diseases drug-target interaction event events facilitate functional annotation help host cell human cell identify immune response IMPROVE Infectious disease mechanism mechanisms Organoid performed platform profile Protein protein expression provided Quantitative data regulate Regulatory Research resource RNA RNA-seq dataset severity splicing tissues transcriptional virus [DOI] 10.1186/s12967-022-03699-8 PMC 바로가기
TIMELESS is a key gene mediating thrombogenesis in COVID-19 and antiphospholipid syndromeArticle Published on 2022-10-142022-11-15 Journal: Scientific Reports [Category] 유전자 메커니즘, 진단, [키워드] Analysis analysis antibody autoantibody autophagy gene Bioinformatics analysis Cell circadian clock Coagulation contribute COVID-19 COVID-19 patient COVID-19 patients Critically ill cytoHubba Cytoscape software dataset Differentially expressed genes evaluated expression Genes Genetic GSK3B identify Immune-mediated Immunotherapy increased risk Interference investigated Kyoto mechanism Mild Modification mononuclear cell ontology term pathway Patient patients protein-protein interaction Proteins regulate severe COVID-19 severe COVID-19 patient severe COVID-19 patients severity suggested Symptom syndrome therapeutic potential thrombosis Transcriptome were used with COVID-19 [DOI] 10.1038/s41598-022-21694-3 PMC 바로가기
A Review: Highlighting the Links between Epigenetics, COVID-19 Infection, and Vitamin DArticle Published on 2022-10-142022-11-16 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Apoptosis changes in Chromatin structure contribute COVID-19 COVID-19 infections disease risk drug Effect Epigenetic epigenetic modification epigenetics Evidence Gene Expression Health help highlight Host immune response Immunity immunomodulatory effect indicate individual Infection Inflammation involved mechanisms Modification modulated multifunctional outcomes pathophysiology Prevent proliferation receptor receptor function reduced regulate SARS-CoV-2 target therapeutic therapeutic drug Treatment Vaccine viral outbreak virus Vitamin D vitamin D. while [DOI] 10.3390/ijms232012292 PMC 바로가기